Unrecognized androgen secreting huge adrenocortical carcinoma in need of urgent surgery

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Androgen secreting adrenocortical tumours.

BACKGROUND Androgen secreting adrenocortical tumours are rare in children and the determination of their malignant potential can be difficult. OBJECTIVES To assess the presentation, histology, and clinical behaviour of these tumours. SETTING Two tertiary referral centres. STUDY DESIGN Retrospective analysis of children diagnosed with an androgen secreting adrenocortical tumour between 197...

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Giant adrenal myelolipoma associated with 21-hydroxylase deficiency: unusual association mimicking an androgen-secreting adrenocortical carcinoma.

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Outcomes after resection of cortisol-secreting adrenocortical carcinoma.

BACKGROUND We sought to define the impact of cortisol-secreting status on outcomes after surgical resection of adrenocortical carcinoma (ACC). METHODS The U.S ACC group database was queried to identify patients who underwent ACC resection between 1993 and 2014. The short-term and long-term outcomes were assessed. RESULTS The incidence of all functional and cortisol-secreting tumors was 40.6...

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Adrenocortical carcinoma secreting cortisol, androgens and aldosterone: a case report

INTRODUCTION Adrenocortical carcinoma is a rare malignancy with a poor prognosis and presents with mass effects and less often with signs of hormone excess (approximately 60% of all adrenocortical carcinoma's). Hormonally active adrenocortical carcinomas most commonly secrete cortisol while the co-secretion of multiple steroid hormones is rare. CASE PRESENTATION We report the case of a 59 yea...

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Sex steroids in androgen-secreting adrenocortical tumors: clinical and hormonal features in comparison with non-tumoral causes of androgen excess.

OBJECTIVE Adrenocortical tumors (ACT) account for no more than 0.2% of the causes of androgen excess (AE). Conversely, these rare tumors have a very poor prognosis. It is difficult and important to exclude this diagnosis whenever there is AE. DESIGN Retrospective investigation of androgen profiles in a large consecutive series of androgen-secreting (AS) ACT to assess their relative diagnostic...

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ژورنال

عنوان ژورنال: Journal of Case Reports and Images in Oncology

سال: 2016

ISSN: 2582-1318

DOI: 10.5348/z10-2016-29-cr-20